The use of Antidotes
is since the early history of medicine. Antidote is agent that counters the effects of poison or over dosage by another drug. It helps in neutralizing the dangerous effects of a poison in body and has scientific approaches that have been taken to assess the therapeutic value of antidotes. Most important development are related to the role of antidotes in the management of poisoning cases that have incurred in past few years. Various studies for instances, toxicodynamic and toxicokinetic is expected to help in improving the approach taken for the development and evaluation of antidotes.
In addition due to increasing global concern for the effectiveness of antidotes has resulted in the exchange of knowledge, scientific information and clinical experience between health care professionals and scientists from different parts of the world. The evolution of antidotal therapy has been characterized with the help of new antidotes such as monoclonal antibodies, also by accurate scientific approach for the effectiveness and the complications that may occur, by novel applications of existing pharmaceuticals, and by increased cooperation and collaboration at global level.
In the last several years, global market of antidotes developed rapidly. In 2018, global revenue of antidotes is nearly 7600 Million USD. And the global growth rate is at 3.16% from 2014 to 2018. And it will be 9437.72 Million USD in 2025, with a CAGR 3.14% from 2018 to 2025.
The classification of antidotes includes chemical antidotes, physical antidotes, pharmacological antidotes and the proportion of chemical antidotes in 2018 is about 46%, and following is pharmacological antidotes with share about 30%
Antidotes are widely used for pesticide poisoning, heavy metal poisoning, animal bites poisoning, cyanide poisoning, etc. The most proportion of antidotes used to treat pesticide poisoning, and the revenue in 2018 is 2093 Million USD.
North America is the largest consumption place, with a consumption market share nearly 33% in 2018. Following North America, Europe is the second largest consumption place with the consumption market share of 25.81%.
Market competition is intense. Roche, Pfizer, Bayer, Johnson & Johnson, Novartis, Eli Lilly, Teva, Boehringer Ingelheim are the leaders of the industry, and they command prominent positions in the global market owing to their strong geographic presence, excellent distribution networks, and the financial power to acquire niche device developers across the globe.